Interventions for managing medication-related osteonecrosis of the jaw

Interventions for managing medication-related osteonecrosis of the jaw

Cochrane Review 19 SoF Entries

Summary of Findings

Key results and quality assessments using GRADE methodology

Outcome Effect Participants Studies Certainty
Incidence of infection of dental healthcare providers
no rinsing
nan - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment –operator level
no rinsing
nan - - Not assessed
Reduction in level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment
no rinsing
nan - - Not assessed
Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity
no rinsing
nan - - Not assessed
nan
nan
nan - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – combined patient and operator level
water
632.94 - - Not assessed
Reduction in the level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – combined operator, assistant and patient level
water
101.1 - - Not assessed
Reduction in level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment
water
nan - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – operator level
saline
21.33 - - Not assessed
Reduction in the level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment
saline
nan - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – assistant level
essential oils/herbal mouthwash
12.21 - - Not assessed
Reduction in level of contamination by particles ? 5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment
essential oils/herbal mouthwash
nan - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – operator level (aerobic cultures)
povidone iodine
10.75 - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – operator level (aerobic and anaerobic cultures combined)
povidone iodine
4.7 - - Not assessed
Reduction in level of contamination by particles ≤ 5 µm (droplet nuclei) at distances of ≥ 2 m from patient's oral cavity in the operative environment – aerobic cultures
povidone iodine
-0.2 - - Not assessed
Reduction in level of contamination by particles ≤ 5 µm (droplet nuclei) at distances of ≥ 2 m from patient's oral cavity in the operative environment – anaerobic cultures
povidone iodine
0.8 - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – operator
CPC
2.2 - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – assistant
CPC
0.2 - - Not assessed
Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment – combined
non‐tempered CHX
10.8 - - Not assessed
GRADE Certainty of Evidence:
High Very confident in the effect estimate
Moderate Moderately confident in the effect estimate
Low Limited confidence in the effect estimate
Very Low Very little confidence in the effect estimate

Review Information

Review ID: CD013826
Outcomes: 19 assessed

Related Content

Evidence Quality Distribution:
Not assessed: 19