Interventions for managing medication-related osteonecrosis of the jaw
Interventions for managing medication-related osteonecrosis of the jaw
Cochrane Review
11 SoF Entries
Summary of Findings
Key results and quality assessments using GRADE methodology
| Outcome | Effect | Participants | Studies | Certainty |
|---|---|---|---|---|
|
Oral mucositis (moderate + severe) (BMT/SCT after conditioning for haematological cancers)
Placebo |
0.89 | - | - | Not assessed |
|
Oral mucositis (moderate + severe) (RT to head and neck with cisplatin/5FU)
Placebo |
0.91 | - | - | Not assessed |
|
Oral mucositis (moderate + severe) (CT alone for mixed cancers)
Placebo |
0.56 | - | - | Not assessed |
|
Oral mucositis (severe) (BMT/SCT after conditioning for haematological cancers)
Placebo |
0.85 | - | - | Not assessed |
|
Oral mucositis (severe) (RT to head and neck with cisplatin/5FU)
Placebo |
0.79 | - | - | Not assessed |
|
Oral mucositis (severe) (CT alone for mixed cancers)
Placebo |
0.3 | - | - | Not assessed |
|
Adverse events
Placebo |
nan | - | - | Not assessed |
|
Oral mucositis (moderate + severe) (RT to head and neck)
Placebo/no treatment |
0.72 | - | - | Not assessed |
|
Oral mucositis (severe) (BMT/SCT after conditioning for mixed cancers)
Placebo/no treatment |
0.74 | - | - | Not assessed |
|
Oral mucositis (severe) (RT to head and neck)
Placebo/no treatment |
0.31 | - | - | Not assessed |
|
Oral mucositis (moderate + severe) (CT alone for breast cancer)
Placebo/no treatment |
0.33 | - | - | Not assessed |
GRADE Certainty of Evidence:
High
Very confident in the effect estimate
Moderate
Moderately confident in the effect estimate
Low
Limited confidence in the effect estimate
Very Low
Very little confidence in the effect estimate
Review Information
| Review ID: | CD011990 |
| Outcomes: | 11 assessed |
Related Content
Evidence Quality Distribution:
Not assessed:
11