Fluoride supplements (tablets drops gums or lozenges) for preventing dental caries in children

Cochrane Review 16 SoF Entries

Key results and quality assessments using GRADE methodology

Outcome	Effect	Participants	Studies	Certainty
Cancer development at 24 months from start of treatment (treatment lasted 12 months) Placebo	0.11	-	-	Not assessed
Clinical resolution (not completely resolved) at 4 to 12 months Placebo	nan	-	-	Not assessed
Histological changes (not improved) at 3 months Placebo	0.43	-	-	Not assessed
Safety of the intervention at 4 to 12 months Placebo	nan	-	-	Not assessed
Clinical resolution (not completely resolved) at 5 to 12 months Placebo	nan	-	-	Not assessed
Histological changes (not improved) at 5 months (treatment lasted 3 months) Placebo	0.24	-	-	Not assessed
Safety of the intervention at 5 to 12 months Placebo	nan	-	-	Not assessed
Cancer development Placebo	nan	-	-	Not assessed
Clinical resolution (not completely resolved) at 3 months Placebo	nan	-	-	Not assessed
Histological changes (not improved) Placebo	nan	-	-	Not assessed
Safety of the intervention over 3 months Placebo	nan	-	-	Not assessed
Clinical resolution (not completely resolved) at 3 to 6 months Placebo	nan	-	-	Not assessed
Cancer development up to 7 years Placebo	3	-	-	Not assessed
Clinical resolution (not completely resolved) at 6 months Placebo	1	-	-	Not assessed
Histological changes (not improved) at 6 months Placebo	Not measured	-	-	Not assessed
Safety of the intervention up to 6 months Placebo	Not measured	-	-	Not assessed

High Very confident in the effect estimate

Moderate Moderately confident in the effect estimate

Low Limited confidence in the effect estimate

Very Low Very little confidence in the effect estimate

Review ID:	CD001829
Outcomes:	16 assessed